Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA.
Antibacterial drugs with novel scaffolds and new mechanisms of action are desperately needed to address the growing problem Patch of antibiotic resistance.The periplasmic oxidative folding system in Gram-negative bacteria represents a possible target for anti-virulence antibacterials.By targeting virulence rather than viability, development of resi